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CD4 Antigens MeSH Descriptor Data 2022


MeSH Heading
CD4 Antigens
Tree Number(s)
D12.776.543.750.705.852.420.810.500
D12.776.543.750.830.700.025
D23.050.301.264.894.100
D23.101.100.894.100
Unique ID
D015704
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015704
Annotation
for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN
Scope Note
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
Entry Term(s)
Antigens, CD4
CD4 Antigen
CD4 Molecule
CD4 Receptor
CD4 Receptors
Receptors, CD4
Receptors, Surface CD4
Surface CD4 Receptor
T4 Antigens, T-Cell
Registry Number
0
NLM Classification #
QW 573
Previous Indexing
Antigens, Differentiation, T-Lymphocyte (1988-1989)
Antigens, Surface (1979-1987)
Receptors, Antigen, T-Cell (1980-1989)
Receptors, Virus (1979-1989)
See Also
CD4-CD8 Ratio
HIV Envelope Protein gp120
Immunoglobulin Domains
Public MeSH Note
2018; see ANTIGENS, CD4 1990-2017 and ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989
History Note
2018 (1989); use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989
Date Established
1990/01/01
Date of Entry
1989/06/19
Revision Date
2021/06/30
CD4 Antigens Preferred
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