MeSH Browser

MeSH Heading: Interferon-gamma
Tree Number(s): D12.644.276.374.440.893; D12.644.276.374.480.615.350; D12.776.467.374.440.893; D12.776.467.374.480.615.350; D23.529.374.440.893; D23.529.374.480.615.350
Unique ID: D007371
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007371
Scope Note: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Entry Term(s): Interferon Type II; Interferon, Immune; Interferon, gamma; Type II Interferon; gamma-Interferon
Pharm Action: Antiviral Agents
CAS Type 1 Name: Interferon gamma (human lymphocyte protein moiety reduced)
Previous Indexing: Interferons (1966-1982)
See Also: Interferon-gamma Release Tests
Public MeSH Note: 2009; see INTERFERON TYPE II 1984-2008, see INTERFERON, GAMMA 1983-1990
History Note: 2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990
Date Established: 1983/01/01
Date of Entry: 1982/05/19
Revision Date: 2015/06/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011490
Scope Note: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Terms: Interferon-gamma Preferred Term
Term UI T022085
Date03/30/1990
LexicalTag NON
ThesaurusID NLM (1991); Interferon Type II
Term UI T022088
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1983); Interferon, gamma
Term UI T022083
Date02/12/1991
LexicalTag NON
ThesaurusID NLM (1992); Interferon, Immune
Term UI T022086
Date05/19/1982
LexicalTag NON
ThesaurusID UNK (19XX); Type II Interferon
Term UI T022087
Date03/19/1991
LexicalTag NON
ThesaurusID NLM (1992); gamma-Interferon
Term UI T022084
Date03/19/1991
LexicalTag NON
ThesaurusID NLM (1992)

Interferon-gamma MeSH Descriptor Data 2024