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Receptors, Formyl Peptide MeSH Descriptor Data 2025
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
Entry Version
RECEPT FORMYL PEPTIDE
Entry Term(s)
Chemoattractant Receptor
Chemotactic Peptide Receptor
F-Chemotactic Peptide Receptor
FMLP Receptor
Formyl Peptide Receptor
N-Formylmethionyl Peptide Receptor
N-formyl Hexapeptide Receptor
Receptor, Chemotactic Peptide
fMet-Leu-Phe Receptor
Registry Numbers
0
Previous Indexing
Receptors, Immunologic (1980-2003)
Receptors, Peptide (1980-2003)
Public MeSH Note
2004; CHEMOTACTIC PEPTIDE RECEPTOR (now RECEPTORS, FORMYL PEPTIDE) was indexed under RECEPTORS, IMMUNOLOGIC & RECEPTORS, PEPTIDE 1980-2003
History Note
2004; use RECEPTORS, FORMYL PEPTIDE (NM) 1980-2003
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.