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Receptor, PAR-2 MeSH Descriptor Data 2022


MeSH Heading
Receptor, PAR-2
Tree Number(s)
D12.776.543.750.695.035
D12.776.543.750.792.249
Unique ID
D044464
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D044464
Scope Note
A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence.
Entry Version
RECEPT PAR 2
Entry Term(s)
PAR-2 Receptor
PAR2 Receptor
Protease-Activated Receptor 2
Proteinase Activated Receptor 2
Receptor, Trypsin
Trypsin Receptor
Trypsin Receptors
Registry Number
0
Previous Indexing
Receptors, Thrombin (1994-2003)
Public MeSH Note
2004; PROTEINASE ACTIVATED RECEPTOR 2 (now RECEPTOR, PAR-2) was indexed under RECEPTORS, THROMBIN 1994-2003; TRYPSIN RECEPTOR (now RECEPTOR, PAR-2) was indexed under RECEPTORS, CELL SURFACE 1986-2003
History Note
2004; use RECEPTOR, PAR-2 (NM) 1994-2003; for TRYPSIN RECEPTOR use RECEPTOR, PAR-2 (NM) 1986-2003
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2016/06/17
Receptor, PAR-2 Preferred
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