MeSH Browser

MeSH Heading: Receptors, Opioid
Tree Number(s): D12.776.543.750.695.620; D12.776.543.750.720.600.610; D12.776.543.750.750.555.610
Unique ID: D011957
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011957
Scope Note: Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
Entry Version: RECEPT OPIOID
Entry Term(s): Endorphin Receptor; Endorphin Receptors; Enkephalin Receptor; Enkephalin Receptors; Narcotic Receptors; Normorphine Receptors; Opiate Receptor; Opiate Receptors; Opioid Receptor; Opioid Receptors; Receptors, Endorphin; Receptors, Enkephalin; Receptors, Narcotic; Receptors, Normorphine; Receptors, Opiate; Receptors, beta-Endorphin; beta-Endorphin Receptor
Previous Indexing: Narcotics (1966-1976); Receptors, Drug (1966-1976)
Public MeSH Note: 94; was RECEPTORS, ENDORPHIN 1980-93; was RECEPTORS, NARCOTIC 1977-79
Online Note: use RECEPTORS, OPIOID to search RECEPTORS, ENDORPHIN 1980-93 & RECEPTORS, NARCOTIC 1977-79
History Note: 94; was RECEPTORS, ENDORPHIN 1980-93; was RECEPTORS, NARCOTIC 1977-79
Entry Combination: antagonists & inhibitors:Narcotic Antagonists
Date Established: 1977/01/01
Date of Entry: 1976/05/03
Revision Date: 2016/06/17

Entry Combination: antagonists & inhibitors:Narcotic Antagonists
Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Apelin Receptors [D12.776.543.750.695.006]
        
        Calcitonin Receptor-Like Protein [D12.776.543.750.695.011]
        
        Frizzled Receptors [D12.776.543.750.695.017]
        
        Glucagon-Like Peptide Receptors [D12.776.543.750.695.021]
        
        Receptors, Kisspeptin-1 [D12.776.543.750.695.022]
        
        Orexin Receptors [D12.776.543.750.695.023]
        
        Receptor, Anaphylatoxin C5a [D12.776.543.750.695.024]
        
        Receptor, PAR-2 [D12.776.543.750.695.035]
        
        Receptors, Adrenomedullin [D12.776.543.750.695.041]
        
        Receptors, Angiotensin [D12.776.543.750.695.047]
        
        Receptors, Bombesin [D12.776.543.750.695.070]
        
        Receptors, Bradykinin [D12.776.543.750.695.080]
        
        Receptors, Calcitonin [D12.776.543.750.695.100]
        
        Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.695.105]
        
        Receptors, Calcium-Sensing [D12.776.543.750.695.115]
        
        Receptors, Cannabinoid [D12.776.543.750.695.125]
        
        Receptors, Catecholamine [D12.776.543.750.695.150]
        
        Receptors, Chemokine [D12.776.543.750.695.160]
        
        Receptors, Cholecystokinin [D12.776.543.750.695.170]
        
        Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.695.180]
        
        Receptors, Eicosanoid [D12.776.543.750.695.200]
        
        Receptors, Endothelin [D12.776.543.750.695.220]
        
        Receptors, Formyl Peptide [D12.776.543.750.695.235]
        
        Receptors, FSH [D12.776.543.750.695.250]
        
        Receptors, GABA-B [D12.776.543.750.695.300]
        
        Receptors, Galanin [D12.776.543.750.695.315]
        
        Receptors, Ghrelin [D12.776.543.750.695.322]
        
        Receptors, Glucagon [D12.776.543.750.695.330]
        
        Receptors, Histamine H1 [D12.776.543.750.695.350]
        
        Receptors, Histamine H2 [D12.776.543.750.695.355]
        
        Receptors, Histamine H4 [D12.776.543.750.695.358]
        
        Receptors, Islet Amyloid Polypeptide [D12.776.543.750.695.360]
        
        Receptors, LH [D12.776.543.750.695.400]
        
        Receptors, LHRH [D12.776.543.750.695.410]
        
        Receptors, Lysophospholipid [D12.776.543.750.695.420]
        
        Receptors, Melanocortin [D12.776.543.750.695.430]
        
        Receptors, Melatonin [D12.776.543.750.695.440]
        
        Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
        
        Receptors, Muscarinic [D12.776.543.750.695.475]
        
        Receptors, Neuropeptide Y [D12.776.543.750.695.500]
        
        Receptors, Neurotensin [D12.776.543.750.695.550]
        
        Receptors, Odorant [D12.776.543.750.695.600]
        
        Receptors, Opioid [D12.776.543.750.695.620]
        
        Receptors, Opioid, delta [D12.776.543.750.695.620.200]
        
        Receptors, Opioid, kappa [D12.776.543.750.695.620.400]
        
        Receptors, Opioid, mu [D12.776.543.750.695.620.550]
        
        Receptors, sigma [D12.776.543.750.695.620.775]
        
        Nociceptin Receptor [D12.776.543.750.695.620.887]
        
        Receptors, Oxytocin [D12.776.543.750.695.630]
        
        Receptors, Parathyroid Hormone [D12.776.543.750.695.650]
        
        Receptors, Pheromone [D12.776.543.750.695.660]
        
        Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide [D12.776.543.750.695.665]
        
        Receptors, Purinergic [D12.776.543.750.695.700]
        
        Receptors, Serotonin [D12.776.543.750.695.800]
        
        Receptors, Somatostatin [D12.776.543.750.695.850]
        
        Receptors, Tachykinin [D12.776.543.750.695.862]
        
        Receptors, Thrombin [D12.776.543.750.695.875]
        
        Receptors, Vasopressin [D12.776.543.750.695.910]
        
        Rhodopsin [D12.776.543.750.695.955]
        
        Xenotropic and Polytropic Retrovirus Receptor [D12.776.543.750.695.977]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Neuropeptide [D12.776.543.750.720.600]
        
        Orexin Receptors [D12.776.543.750.720.600.074]
        
        Receptors, Bombesin [D12.776.543.750.720.600.200]
        
        Receptors, Bradykinin [D12.776.543.750.720.600.220]
        
        Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.720.600.260]
        
        Receptors, Cholecystokinin [D12.776.543.750.720.600.270]
        
        Receptors, Corticotropin [D12.776.543.750.720.600.285]
        
        Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.720.600.290]
        
        Receptors, FSH [D12.776.543.750.720.600.370]
        
        Receptors, Galanin [D12.776.543.750.720.600.410]
        
        Receptors, LH [D12.776.543.750.720.600.450]
        
        Receptors, LHRH [D12.776.543.750.720.600.460]
        
        Receptors, Neuropeptide Y [D12.776.543.750.720.600.540]
        
        Receptors, Neurotensin [D12.776.543.750.720.600.560]
        
        Receptors, Opioid [D12.776.543.750.720.600.610]
        
        Receptors, Opioid, delta [D12.776.543.750.720.600.610.200]
        
        Receptors, Opioid, kappa [D12.776.543.750.720.600.610.400]
        
        Receptors, Opioid, mu [D12.776.543.750.720.600.610.550]
        
        Receptors, sigma [D12.776.543.750.720.600.610.775]
        
        Nociceptin Receptor [D12.776.543.750.720.600.610.887]
        
        Receptors, Oxytocin [D12.776.543.750.720.600.630]
        
        Receptors, Prolactin [D12.776.543.750.720.600.710]
        
        Receptors, Somatostatin [D12.776.543.750.720.600.760]
        
        Receptors, Tachykinin [D12.776.543.750.720.600.830]
        
        Receptors, Thyrotropin [D12.776.543.750.720.600.850]
        
        Receptors, Thyrotropin-Releasing Hormone [D12.776.543.750.720.600.860]
        
        Receptors, Vasoactive Intestinal Peptide [D12.776.543.750.720.600.915]
        
        Receptors, Vasopressin [D12.776.543.750.720.600.925]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Peptide [D12.776.543.750.750]
        
        Receptors, Neuropeptide [D12.776.543.750.750.555]
        
        Orexin Receptors [D12.776.543.750.750.555.074]
        
        Receptors, Bombesin [D12.776.543.750.750.555.200]
        
        Receptors, Bradykinin [D12.776.543.750.750.555.220]
        
        Receptors, Calcitonin Gene-Related Peptide [D12.776.543.750.750.555.260]
        
        Receptors, Cholecystokinin [D12.776.543.750.750.555.270]
        
        Receptors, Corticotropin [D12.776.543.750.750.555.285]
        
        Receptors, Corticotropin-Releasing Hormone [D12.776.543.750.750.555.290]
        
        Receptors, FSH [D12.776.543.750.750.555.370]
        
        Receptors, Galanin [D12.776.543.750.750.555.410]
        
        Receptors, LH [D12.776.543.750.750.555.450]
        
        Receptors, LHRH [D12.776.543.750.750.555.460]
        
        Receptors, Neuropeptide Y [D12.776.543.750.750.555.540]
        
        Receptors, Neurotensin [D12.776.543.750.750.555.560]
        
        Receptors, Opioid [D12.776.543.750.750.555.610]
        
        Receptors, Opioid, delta [D12.776.543.750.750.555.610.200]
        
        Receptors, Opioid, kappa [D12.776.543.750.750.555.610.400]
        
        Receptors, Opioid, mu [D12.776.543.750.750.555.610.550]
        
        Receptors, sigma [D12.776.543.750.750.555.610.775]
        
        Nociceptin Receptor [D12.776.543.750.750.555.610.887]
        
        Receptors, Oxytocin [D12.776.543.750.750.555.630]
        
        Receptors, Prolactin [D12.776.543.750.750.555.710]
        
        Receptors, Somatostatin [D12.776.543.750.750.555.760]
        
        Receptors, Somatotropin [D12.776.543.750.750.555.770]
        
        Receptors, Tachykinin [D12.776.543.750.750.555.830]
        
        Receptors, Thyrotropin [D12.776.543.750.750.555.850]
        
        Receptors, Thyrotropin-Releasing Hormone [D12.776.543.750.750.555.860]
        
        Receptors, Vasoactive Intestinal Peptide [D12.776.543.750.750.555.915]
        
        Receptors, Vasopressin [D12.776.543.750.750.555.925]

Receptors, Opioid Preferred

Concept UI: M0018578
Scope Note: Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
Terms: Receptors, Opioid Preferred Term
Term UI T035390
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1977); Opiate Receptors
Term UI T035386
Date05/12/1992
LexicalTag NON
ThesaurusID NLM (1993); Receptors, Opiate
Term UI T035387
Date05/03/1979
LexicalTag NON
ThesaurusID UNK (19XX); Opioid Receptor
Term UI T035388
Date03/04/1993
LexicalTag NON
ThesaurusID NLM (1994); Opioid Receptors
Term UI T035389
Date12/28/1992
LexicalTag NON
ThesaurusID NLM (1994); Opiate Receptor
Term UI T035385
Date03/04/1993
LexicalTag NON
ThesaurusID NLM (1994)

beta-Endorphin Receptor Narrower

Receptors, Normorphine Narrower

Receptors, Narcotic Broader

Receptors, Endorphin Narrower

Enkephalin Receptor Narrower

Receptors, Opioid MeSH Descriptor Data 2024