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Receptors, sigma MeSH Descriptor Data 2023


MeSH Heading
Receptors, sigma
Tree Number(s)
D12.776.543.750.695.620.775
D12.776.543.750.720.600.610.775
D12.776.543.750.750.555.610.775
Unique ID
D017480
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017480
Scope Note
A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.
Entry Version
RECEPT SIGMA
Entry Term(s)
Opioid Receptors, sigma
Receptors, Opioid, sigma
Receptors, sigma Opioid
sigma Receptor
sigma Receptors
Registry Number
0
Previous Indexing
Receptors, Endorphin (1981-1992)
Public MeSH Note
93; SIGMA RECEPTOR was indexed under RECEPTORS, ENDORPHIN 1981-92
Online Note
use RECEPTORS, SIGMA (NM) to search SIGMA RECEPTOR 1981-92
History Note
93; was SIGMA RECEPTOR (NM) 1981-92
Date Established
1993/01/01
Date of Entry
1992/05/22
Revision Date
2016/06/17
Receptors, sigma Preferred
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