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Receptors, Histamine H2 MeSH Descriptor Data 2025


MeSH Heading
Receptors, Histamine H2
Tree Number(s)
D12.776.543.750.670.450.400
D12.776.543.750.695.355
D12.776.543.750.720.480.400
Unique ID
D011970
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011970
Annotation
receptors for the non-classical antihistaminics (HISTAMINE H2 ANTAGONISTS)
Scope Note
A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
Entry Version
RECEPT HISTAMINE H2
Entry Term(s)
H2 Receptors
Histamine H2 Receptors
Receptors, H2
Registry Numbers
0
Previous Indexing
Histamine (1966-1976)
Receptors, Drug (1970-1976)
Public MeSH Note
87; was see under RECEPTORS, HISTAMINE 1977-86
History Note
87(77); was see under RECEPTORS, HISTAMINE 1977-86
Entry Combination
agonists:Histamine Agonists
antagonists & inhibitors:Histamine H2 Antagonists
Date Established
1987/01/01
Date of Entry
1976/05/05
Revision Date
2019/05/24
Receptors, Histamine H2 Preferred
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