NLM Logo

Receptors, Enterotoxin MeSH Descriptor Data 2022


MeSH Heading
Receptors, Enterotoxin
Tree Number(s)
D08.811.520.650.600.500.250
D12.776.543.750.700.250
D12.776.543.750.750.330
Unique ID
D000074261
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074261
Scope Note
Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.
Entry Term(s)
Enterotoxin Receptor
Enterotoxin Receptors
Enterotoxin-Guanylin Receptor
Enterotoxin-Guanylin Receptors
GC-C Receptor
GC-C Receptors
Guanyl Cyclase-C Receptor
Guanyl Cyclase-C Receptors
Guanylin-Uroguanylin Receptor
Guanylin-Uroguanylin Receptors
Guanylyl Cyclase C
Heat-Stable Enterotoxin Receptor
Heat-Stable Enterotoxin Receptors
Receptor, Enterotoxin
Receptor, Guanyl Cyclase-C
Receptors, Guanyl Cyclase-C
Registry Number
EC 4.6.1.2
Public MeSH Note
2018; RECEPTORS, ENTEROTOXIN was indexed under GUANYLATE CYCLASE 1981-2011; RECEPTORS, IMMUNOLOGIC 1981-1988; RECEPTORS, ENDOGENOUS SUBSTANCES 1989-1993; RECEPTORS, PEPTIDE 1994-2017 and RECEPTORS, GUANYLATE-CYCLASE COUPLED 2006-2017
History Note
2018 (1981)
Entry Combination
agonists:Guanylyl Cyclase C Agonists
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2018/06/20
Receptors, Enterotoxin Preferred
page delivered in 0.157s