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Neurexins MeSH Descriptor Data 2024


MeSH Heading
Neurexins
Tree Number(s)
D09.400.430.890.200.250.640
D12.776.395.550.200.250.640
D12.776.543.550.200.250.760
D12.776.631.609
D23.050.301.350.250.760
Unique ID
D000096784
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000096784
Scope Note
Presynaptic cell-adhesion molecules that bind postsynaptic NEUROLIGINS to form calcium-dependent trans-synaptic adhesions. Neurexins recruit synaptic scaffolding proteins via their PDZ DOMAINS. Distribution and interaction with neuroligins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neurexins are associated with cognitive diseases such AUTISM SPECTRUM DISORDER; SCHIZOPHRENIA and Pitt-Hopkins-like syndrome 2.
Registry Number
0
Previous Indexing
Nerve Tissue Proteins (1992-2023)
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/04/05
Neurexins Preferred
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