MeSH Browser

MeSH Heading: Fragile X Messenger Ribonucleoprotein 1
Tree Number(s): D12.776.157.725.061; D12.776.631.299; D12.776.664.962.124
Unique ID: D051860
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051860
Scope Note: A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
Entry Term(s): FMR1 Protein; FMRP Protein; Fragile X Mental Retardation Protein; Fragile X Mental Retardation-1 Protein
Registry Numbers: 139135-51-6
Public MeSH Note: 2006; FRAGILE X MENTAL RETARDATION PROTEIN was indexed under NERVE TISSUE PROTEINS & RNA-BINDING PROTEINS 1991-2005
History Note: 2006(1991)
Entry Combination: deficiency:Fragile X Syndrome
Date Introduced: 2006/01/01
Last Updated: 2026/01/01

Entry Combination: deficiency:Fragile X Syndrome
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0188653
Registry Numbers: 139135-51-6
Scope Note: A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
Terms: Fragile X Messenger Ribonucleoprotein 1 Preferred Term
Term UI T001146136
Date12/04/2024
LexicalTag NON
ThesaurusID NLM (2025); FMR1 Protein
Term UI T001146589
Date01/14/2025
LexicalTag NON
ThesaurusID NLM (2026); FMRP Protein
Term UI T218656
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); Fragile X Mental Retardation Protein
Term UI T633436
Date03/16/2005
LexicalTag NON
ThesaurusID NLM (2006); Fragile X Mental Retardation-1 Protein
Term UI T218657
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Fragile X Messenger Ribonucleoprotein 1 MeSH Descriptor Data 2026