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Iron Regulatory Protein 2 MeSH Descriptor Data 2022


MeSH Heading
Iron Regulatory Protein 2
Tree Number(s)
D08.811.520.241.300.050.750
D12.776.157.427.374.375.961
D12.776.157.725.437
D12.776.494.750
D12.776.556.579.374.375.962
D12.776.664.962.437
Unique ID
D035942
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D035942
Scope Note
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.
Entry Term(s)
IRE-BP2
IREB2 Protein
IRP-2 RNA-binding protein
IRP2 Protein
Iron-Responsive-Element Binding Protein 2
Registry Number
EC 4.2.1.3
Previous Indexing
Iron-Sulfur Proteins (1995-2002)
Ribonucleoproteins (1995-2002)
Public MeSH Note
2003; IRON REGULATORY PROTEIN 2, IRE-BP2 & IRP-2 RNA-BINDING PROTEIN were indexed under RNA-BINDING PROTEINS & IRON-SULFUR PROTEINS 1995-2002
History Note
2003; for IRON REGULATORY PROTEIN 2, IRE-BP2 & IRP-2 RNA-BINDING PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2006/07/05
Iron Regulatory Protein 2 Preferred
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