MeSH Browser

MeSH Heading: Spinocerebellar Ataxias
Tree Number(s): C10.228.140.252.190.530; C10.228.140.252.700.700; C10.228.854.787.875; C10.574.500.825.700; C10.597.350.090.500.530; C16.320.400.780.875
Unique ID: D020754
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020754
Annotation: SPINOCEREBELLAR ATAXIA TYPE 3 see MACHADO-JOSEPH DISEASE is available
Scope Note: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
Entry Term(s): Autosomal Dominant Cerebellar Ataxia, Type II; Cerebellar Degeneration with Slow Eye Movements; Cerebelloparenchymal Disorder I; Dominantly-Inherited Spinocerebellar Ataxias; Menzel Type OPCA; OPCA with Macular Degeneration and External Ophthalmoplegia; OPCA with Retinal Degeneration; Olivopontocerebellar Atrophy 2; Olivopontocerebellar Atrophy I; Olivopontocerebellar Atrophy II; Olivopontocerebellar Atrophy III; Olivopontocerebellar Atrophy IV; Olivopontocerebellar Atrophy, Holguin Type; SCA1; Schut-Haymaker Type OPCA; Spinocerebellar Ataxia 1; Spinocerebellar Ataxia 2; Spinocerebellar Ataxia 4; Spinocerebellar Ataxia 5; Spinocerebellar Ataxia 6; Spinocerebellar Ataxia 7; Spinocerebellar Ataxia Type 1; Spinocerebellar Ataxia Type 2; Spinocerebellar Ataxia Type 4; Spinocerebellar Ataxia Type 5; Spinocerebellar Ataxia Type 6; Spinocerebellar Ataxia Type 7; Spinocerebellar Ataxia with Slow Eye Movements; Spinocerebellar Ataxia, Autosomal Dominant, with Sensory Axonal Neuropathy; Spinocerebellar Ataxia, Cuban Type; Spinocerebellar Ataxia-1; Spinocerebellar Ataxia-2; Spinocerebellar Ataxia-4; Spinocerebellar Ataxia-5; Spinocerebellar Ataxia-6; Spinocerebellar Ataxia-7; Spinocerebellar Ataxias, Dominantly-Inherited; Spinocerebellar Atrophies; Spinocerebellar Atrophy 2; Spinocerebellar Atrophy I; Spinocerebellar Atrophy II; Spinocerebellar Degeneration with Slow Eye Movements; Type 1 Spinocerebellar Ataxia; Type 2 Spinocerebellar Ataxia; Type 4 Spinocerebellar Ataxia; Type 5 Spinocerebellar Ataxia; Type 6 Spinocerebellar Ataxia; Type 7 Spinocerebellar Ataxia; Wadia Swami Syndrome; Wadia-Swami Syndrome
Previous Indexing: Ataxia/genetics (1965-1999); Cerebellar Diseases (1966-1999); Spinal Cord Diseases (1966-1999); Spinocerebellar Degenerations (1987-1999)
See Also: Ataxin-1; Ataxin-2; Ataxin-3; Ataxin-7; Ataxins
Public MeSH Note: 2000; see SPINOCEREBELLAR DEGENERATION 1987-1999
History Note: 2000; use SPINOCEREBELLAR DEGENERATION 1987-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2021/05/10

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Cerebellar Diseases [C10.228.140.252]
      - Cerebellar Ataxia [C10.228.140.252.190]
        
        Spinocerebellar Ataxias [C10.228.140.252.190.530]
        
        Ataxia Telangiectasia [C10.228.140.252.190.530.060]
        
        Machado-Joseph Disease [C10.228.140.252.190.530.530]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Cerebellar Diseases [C10.228.140.252]
      - Spinocerebellar Degenerations [C10.228.140.252.700]
        
        Friedreich Ataxia [C10.228.140.252.700.150]
        
        Myoclonic Cerebellar Dyssynergia [C10.228.140.252.700.250]
        
        Olivopontocerebellar Atrophies [C10.228.140.252.700.650]
        
        Spinocerebellar Ataxias [C10.228.140.252.700.700]
        
        Machado-Joseph Disease [C10.228.140.252.700.700.500]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Spinal Cord Diseases [C10.228.854]
    - Spinocerebellar Degenerations [C10.228.854.787]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Heredodegenerative Disorders, Nervous System [C10.574.500]
    - Spinocerebellar Degenerations [C10.574.500.825]

Nervous System Diseases [C10]
- Neurologic Manifestations [C10.597]
  - Dyskinesias [C10.597.350]
    - Ataxia [C10.597.350.090]
      - Cerebellar Ataxia [C10.597.350.090.500]
        
        Spinocerebellar Ataxias [C10.597.350.090.500.530]
        
        Ataxia Telangiectasia [C10.597.350.090.500.530.060]
        
        Machado-Joseph Disease [C10.597.350.090.500.530.530]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Heredodegenerative Disorders, Nervous System [C16.320.400]
    - Spinocerebellar Degenerations [C16.320.400.780]

Spinocerebellar Ataxias Preferred

Spinocerebellar Ataxia Type 1 Narrower

Concept UI: M0336155
Terms: Spinocerebellar Ataxia Type 1 Preferred Term
Term UI T370552
Date10/12/1999
LexicalTag NON
ThesaurusID; Olivopontocerebellar Atrophy IV
Term UI T824495
Date06/21/2012
LexicalTag NON
ThesaurusID OMIM (2013); Spinocerebellar Ataxia-1
Term UI T370553
Date10/12/1999
LexicalTag NON
ThesaurusID; Type 1 Spinocerebellar Ataxia
Term UI T370554
Date10/12/1999
LexicalTag NON
ThesaurusID; Spinocerebellar Ataxia 1
Term UI T812471
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Spinocerebellar Atrophy I
Term UI T812472
Date11/15/2011
LexicalTag NON
ThesaurusID; Olivopontocerebellar Atrophy I
Term UI T812474
Date11/15/2011
LexicalTag NON
ThesaurusID; Cerebelloparenchymal Disorder I
Term UI T812480
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Menzel Type OPCA
Term UI T823013
Date06/06/2012
LexicalTag EPO
ThesaurusID OMIM (2013); SCA1
Term UI T843483
Date05/02/2013
LexicalTag NON
ThesaurusID; Schut-Haymaker Type OPCA
Term UI T823014
Date06/06/2012
LexicalTag EPO
ThesaurusID OMIM (2013)

Spinocerebellar Ataxia Type 2 Narrower

Spinocerebellar Ataxia Type 4 Narrower

Spinocerebellar Ataxia Type 5 Narrower

Concept UI: M0336158
Terms: Spinocerebellar Ataxia Type 5 Preferred Term
Term UI T370561
Date10/12/1999
LexicalTag NON
ThesaurusID; Spinocerebellar Ataxia 5
Term UI T812488
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Spinocerebellar Ataxia-5
Term UI T370562
Date10/12/1999
LexicalTag NON
ThesaurusID; Type 5 Spinocerebellar Ataxia
Term UI T370563
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Spinocerebellar Ataxia Type 6 Narrower

Concept UI: M0336159
Terms: Spinocerebellar Ataxia Type 6 Preferred Term
Term UI T370564
Date10/12/1999
LexicalTag NON
ThesaurusID; Spinocerebellar Ataxia-6
Term UI T370565
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Spinocerebellar Ataxia 6
Term UI T812490
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Type 6 Spinocerebellar Ataxia
Term UI T370566
Date10/12/1999
LexicalTag NON
ThesaurusID

Spinocerebellar Ataxia Type 7 Narrower

Concept UI: M0336160
Scope Note: A group of dominantly inherited, predominatly late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
Terms: Spinocerebellar Ataxia Type 7 Preferred Term
Term UI T370567
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); OPCA with Macular Degeneration and External Ophthalmoplegia
Term UI T823018
Date06/06/2012
LexicalTag ABX
ThesaurusID OMIM (2013); OPCA with Retinal Degeneration
Term UI T823019
Date06/06/2012
LexicalTag ABX
ThesaurusID OMIM (2013); Spinocerebellar Ataxia-7
Term UI T370568
Date10/12/1999
LexicalTag NON
ThesaurusID; Type 7 Spinocerebellar Ataxia
Term UI T370569
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Spinocerebellar Ataxia 7
Term UI T812493
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Autosomal Dominant Cerebellar Ataxia, Type II
Term UI T823017
Date06/06/2012
LexicalTag NON
ThesaurusID OMIM (2013); Olivopontocerebellar Atrophy III
Term UI T823016
Date06/06/2012
LexicalTag NON
ThesaurusID OMIM (2013)

Dominantly-Inherited Spinocerebellar Ataxias Narrower

Spinocerebellar Ataxias MeSH Descriptor Data 2024