MeSH Browser

MeSH Heading: Ataxin-2
Tree Number(s): D12.776.157.725.452.125; D12.776.631.069.750; D12.776.660.075.750; D12.776.664.962.452.125
Unique ID: D000067698
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000067698
Scope Note: A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.
Entry Term(s): ATXN2 Protein; Ataxin-2 Protein; Atx-2 Protein; SCA2 Protein; Spinocerebellar Ataxia Type 2 Protein
Registry Number: 0
Previous Indexing: Nerve Tissue Proteins (2005-2015); Proteins (1996-2005)
See Also: Spinocerebellar Ataxias
Public MeSH Note: 2016; ATAXIN-2 was indexed under PROTEINS 1996-2005, and under NERVE TISSUE PROTEINS 2005-2015
History Note: 2016; use SCA2 PROTEIN (NM) 1996-2015
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0394791
Registry Number: 0
Scope Note: A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.
Terms: Ataxin-2 Preferred Term
Term UI T000872353
Date12/17/2014
LexicalTag NON
ThesaurusID NLM (2016); Ataxin-2 Protein
Term UI T000874500
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); Spinocerebellar Ataxia Type 2 Protein
Term UI T000873998
Date01/21/2015
LexicalTag NON
ThesaurusID NLM (2016); ATXN2 Protein
Term UI T000874499
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); Atx-2 Protein
Term UI T000873996
Date01/21/2015
LexicalTag ABX
ThesaurusID NLM (2016); SCA2 Protein
Term UI T000873997
Date01/21/2015
LexicalTag ABX
ThesaurusID NLM (2016)

Ataxin-2 MeSH Descriptor Data 2024