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Proto-Oncogene Proteins c-mdm2 MeSH Descriptor Data 2025


MeSH Heading
Proto-Oncogene Proteins c-mdm2
Tree Number(s)
D08.811.464.938.750.562
D12.776.624.664.700.185
D12.776.660.764
Unique ID
D051736
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051736
Scope Note
An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
Entry Term(s)
Double Minute 2 Protein
MDMX Protein
Mdm-2 Protein
Mdm2 Protein
Murine Double Minute 2 Protein
c-mdm2 Proto-Oncogene Protein
Registry Numbers
EC 2.3.2.27
Public MeSH Note
2006; PROTO-ONCOGENE PROTEINS C-MDM2 was indexed under PROTO-ONCOGENE PROTEINS 2005, & under NUCLEAR PROTEINS 1991-2005, & under NEOPLASM PROTEINS 1991-2004
History Note
2006(1991)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/06/02
Proto-Oncogene Proteins c-mdm2 Preferred
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