- Concept UI
- M0255541
- Registry Numbers
- 0
- Scope Note
- A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR PROTEIN by targeting it for degradation). p14ARF is produced from the beta mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced alpha transcript, is CYCLIN-DEPENDENT KINASE INHIBITOR P16. Both p16 gene products have tumor suppressor functions.
- Terms
-
Tumor Suppressor Protein p14ARF
Preferred Term
Term UI
T632643
Date03/08/2005
LexicalTag
ACX
ThesaurusID
NLM (2006)
-
p(ARF) Protein
Term UI
T435873
Date02/12/2001
LexicalTag
NON
ThesaurusID
NLM (2002)
-
p14(ARF)
Term UI
T285541
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2002)
-
p14ARF
Term UI
T285542
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2002)
-
p14ARF Protein
Term UI
T432577
Date01/08/2001
LexicalTag
ACX
ThesaurusID
NLM (2002)
-
Cdkn2a(p14ARF)
Term UI
T430439
Date12/06/2000
LexicalTag
ACX
ThesaurusID
NLM (2002)