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Mad2 Proteins MeSH Descriptor Data 2023


MeSH Heading
Mad2 Proteins
Tree Number(s)
D12.776.167.313
D12.776.660.526
Unique ID
D064246
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D064246
Scope Note
Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.
Entry Term(s)
Mad2 Mitotic Arrest Deficient-like 1 Proteins
Registry Number
0
Public MeSH Note
2014; was indexed under CELL CYCLE PROTEINS 2000-2013 and NUCLEAR PROTEINS 2005-2013
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/08
Mad2 Proteins Preferred
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