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Securin MeSH Descriptor Data 2022


MeSH Heading
Securin
Tree Number(s)
D12.776.167.504
Unique ID
D064249
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D064249
Scope Note
Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation.
Entry Term(s)
PTTG Protein
Pituitary Tumor-Transforming Gene Protein
Pituitary Tumor-Transforming Proteins
Registry Number
0
Previous Indexing
Neoplasm Proteins (1997-2013)
Public MeSH Note
2014; was indexed under NEOPLASM PROTEINS 1997-2013
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/08
Securin Preferred
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