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Cyclin-Dependent Kinase Inhibitor p16 MeSH Descriptor Data 2022


MeSH Heading
Cyclin-Dependent Kinase Inhibitor p16
Tree Number(s)
D12.644.360.225.200
D12.776.167.187.200
D12.776.476.225.200
D12.776.624.776.355.200
Unique ID
D019941
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019941
Scope Note
A product of the p16 tumor suppressor gene (GENES, P16). It is also called INK4 or INK4A because it is the prototype member of the INK4 CYCLIN-DEPENDENT KINASE INHIBITORS. This protein is produced from the alpha mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced beta transcript, is TUMOR SUPPRESSOR PROTEIN P14ARF. Both p16 gene products have tumor suppressor functions.
Entry Term(s)
CDKN2 Protein
CDKN2A Protein
Cdk4-Associated Protein p16
Cyclin-Dependent Kinase Inhibitor-2A
INK4A Protein
MTS1 Protein
Multiple Tumor Suppressor-1
p16(INK4A)
p16INK4 Protein
p16INK4A Protein
Registry Number
0
Previous Indexing
Carrier Proteins (1994-1997)
See Also
Genes, p16
Tumor Suppressor Protein p14ARF
Public MeSH Note
1998; see PROTEIN P16; CDK4-ASSOCIATED PROTEIN P16 was indexed under CARRIER PROTEINS 1994-1997; P16(INK4A) was indexed under CARRIER PROTEINS 2000-2001
History Note
2006(1994)
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2015/11/23
Cyclin-Dependent Kinase Inhibitor p16 Preferred
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