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Neoplasm Proteins MeSH Descriptor Data 2022


MeSH Heading
Neoplasm Proteins
Tree Number(s)
D12.776.624
Unique ID
D009363
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009363
Annotation
IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4
Scope Note
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Entry Version
NEOPL PROTEINS
Registry Number
0
NLM Classification #
QZ 210
See Also
Antigens, Neoplasm
Biomarkers, Tumor
Date Established
1963/01/01
Date of Entry
1999/01/01
Revision Date
2015/07/13
Neoplasm Proteins Preferred
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