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Huntingtin Protein MeSH Descriptor Data 2024


MeSH Heading
Huntingtin Protein
Tree Number(s)
D12.776.441
Unique ID
D000071058
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071058
Scope Note
A protein that is highly expressed in the nervous system as well as other tissues; its size and structure vary due to polymorphisms. Expanded CAG TRINUCLEOTIDE REPEATS have been identified in the Huntingtin (HD) Gene of patients with HUNTINGTON DISEASE and are associated with abnormal PROTEIN AGGREGATES. Huntingtin interacts with proteins involved in a variety of gene expression and cellular processes; it is also essential for embryonic development.
Entry Term(s)
Huntington Disease Protein
IT15 Protein
Previous Indexing
Nerve Tissue Proteins (2012-2016)
Nuclear Proteins (1994-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/26
Huntingtin Protein Preferred
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