MeSH Browser

MeSH Heading: Huntington Disease
Tree Number(s): C10.228.140.079.545; C10.228.140.380.278; C10.228.662.262.249.750; C10.574.500.497; C16.320.400.430; F03.615.250.400; F03.615.400.390
Unique ID: D006816
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006816
Scope Note: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Entry Version: HUNTINGTON DIS
Entry Term(s): Akinetic-Rigid Variant of Huntington Disease; Chorea, Chronic Progressive Hereditary (Huntington); Chronic Progressive Hereditary Chorea (Huntington); Huntington Chorea; Huntington Chronic Progressive Hereditary Chorea; Huntington Disease, Akinetic-Rigid Variant; Huntington Disease, Juvenile; Huntington Disease, Juvenile-Onset; Huntington Disease, Late Onset; Huntington's Chorea; Huntington's Disease; Juvenile Huntington Disease; Juvenile-Onset Huntington Disease; Late-Onset Huntington Disease; Progressive Chorea, Chronic Hereditary (Huntington); Progressive Chorea, Hereditary, Chronic (Huntington)
NLM Classification #: WL 359.5
Public MeSH Note: 2000; see HUNTINGTON'S DISEASE 1993-1999; for HUNTINGTON DISEASE see HUNTINGTON'S DISEASE 1993-1999, see HUNTINGTON CHOREA 1977-1992, see CHOREA, HEREDITARY 1963-1976
History Note: 2000(1963)
Date Established: 2000/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Basal Ganglia Diseases [C10.228.140.079]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Dementia [C10.228.140.380]

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Movement Disorders [C10.228.662]
    - Dyskinesias [C10.228.662.262]
      - Chorea [C10.228.662.262.249]
        
        Chorea Gravidarum [C10.228.662.262.249.500]
        
        Huntington Disease [C10.228.662.262.249.750]
        
        Neuroacanthocytosis [C10.228.662.262.249.937]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Heredodegenerative Disorders, Nervous System [C10.574.500]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Heredodegenerative Disorders, Nervous System [C16.320.400]

Mental Disorders [F03]
- Neurocognitive Disorders [F03.615]
  - Cognition Disorders [F03.615.250]

Mental Disorders [F03]
- Neurocognitive Disorders [F03.615]
  - Dementia [F03.615.400]

Huntington Disease Preferred

Concept UI: M0010660
Scope Note: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Terms: Huntington Disease Preferred Term
Term UI T020578
Date05/14/1992
LexicalTag EPO
ThesaurusID; Progressive Chorea, Hereditary, Chronic (Huntington)
Term UI T364236
Date11/03/1999
LexicalTag EPO
ThesaurusID NLM (2000); Chronic Progressive Hereditary Chorea (Huntington)
Term UI T368476
Date11/03/1999
LexicalTag EPO
ThesaurusID NLM (2000); Huntington's Chorea
Term UI T020576
Date03/17/1977
LexicalTag EPO
ThesaurusID; Huntington Chorea
Term UI T020577
Date05/11/1992
LexicalTag EPO
ThesaurusID; Huntington's Disease
Term UI T020579
Date01/01/1999
LexicalTag EPO
ThesaurusID; Chorea, Chronic Progressive Hereditary (Huntington)
Term UI T364194
Date11/03/1999
LexicalTag EPO
ThesaurusID NLM (2000); Progressive Chorea, Chronic Hereditary (Huntington)
Term UI T364235
Date11/03/1999
LexicalTag EPO
ThesaurusID; Huntington Chronic Progressive Hereditary Chorea
Term UI T364195
Date11/03/1999
LexicalTag EPO
ThesaurusID

Juvenile Huntington Disease Narrower

Akinetic-Rigid Variant of Huntington Disease Narrower

Huntington Disease, Late Onset Narrower

Huntington Disease MeSH Descriptor Data 2024