MeSH Browser

MeSH Heading: Spinal Muscular Atrophies of Childhood
Tree Number(s): C10.228.854.468.800; C10.574.500.812; C10.574.562.500.750; C10.668.467.500.750; C16.320.400.765
Unique ID: D014897
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D014897
Annotation: infantile, childhood or adolescent: for other, MUSCULAR ATROPHY, SPINAL is available
Scope Note: A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
Entry Version: SPINAL MUSCULAR ATROPHIES CHILDHOOD
Entry Term(s): HMN (Hereditary Motor Neuropathy) Proximal Type I; Infantile Spinal Muscular Atrophy; Juvenile Spinal Muscular Atrophy; Kugelberg-Welander Disease; Kugelberg-Welander Syndrome; Muscular Atrophy, Infantile; Muscular Atrophy, Juvenile; Muscular Atrophy, Spinal, Infantile; Muscular Atrophy, Spinal, Infantile Chronic Form; Muscular Atrophy, Spinal, Intermediate Type; Muscular Atrophy, Spinal, Type I; Muscular Atrophy, Spinal, Type II; Muscular Atrophy, Spinal, Type III; Proximal Hereditary Motor Neuropathy Type I; SMA, Infantile Acute Form; Spinal Muscular Atrophy 1; Spinal Muscular Atrophy Type 2; Spinal Muscular Atrophy Type I; Spinal Muscular Atrophy Type II; Spinal Muscular Atrophy Type III; Spinal Muscular Atrophy, Infantile; Spinal Muscular Atrophy, Juvenile; Spinal Muscular Atrophy, Mild Childhood and Adolescent Form; Spinal Muscular Atrophy, Type 3; Spinal Muscular Atrophy, Type I; Spinal Muscular Atrophy, Type II; Spinal Muscular Atrophy, Type III; Type I Spinal Muscular Atrophy; Type II Spinal Muscular Atrophy; Type III Spinal Muscular Atrophy; Werdnig Hoffman Disease; Werdnig-Hoffmann Disease
NLM Classification #: WS 340.5
Previous Indexing: Muscular Atrophy (1966-1987); Spinal Cord Diseases (1966-1987)
Public MeSH Note: 2000; see WERDNIG-HOFFMAN DISEASE 1991-1999, see MUSCULAR ATROPHY, SPINAL 1988-90
History Note: 2000(1988)
Date Established: 1991/01/01
Date of Entry: 1987/04/28
Revision Date: 2016/02/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Spinal Cord Diseases [C10.228.854]
    - Muscular Atrophy, Spinal [C10.228.854.468]
      - Bulbo-Spinal Atrophy, X-Linked [C10.228.854.468.399]
      - Spinal Muscular Atrophies of Childhood [C10.228.854.468.800]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Heredodegenerative Disorders, Nervous System [C10.574.500]

Nervous System Diseases [C10]
- Neurodegenerative Diseases [C10.574]
  - Motor Neuron Disease [C10.574.562]
    - Muscular Atrophy, Spinal [C10.574.562.500]
      - Bulbo-Spinal Atrophy, X-Linked [C10.574.562.500.374]
      - Spinal Muscular Atrophies of Childhood [C10.574.562.500.750]

Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
  - Motor Neuron Disease [C10.668.467]
    - Muscular Atrophy, Spinal [C10.668.467.500]
      - Bulbo-Spinal Atrophy, X-Linked [C10.668.467.500.186]
      - Spinal Muscular Atrophies of Childhood [C10.668.467.500.750]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Heredodegenerative Disorders, Nervous System [C16.320.400]

Spinal Muscular Atrophies of Childhood Preferred

Juvenile Spinal Muscular Atrophy Narrower

HMN (Hereditary Motor Neuropathy) Proximal Type I Narrower

Muscular Atrophy, Spinal, Type II Narrower

Muscular Atrophy, Spinal, Infantile Chronic Form Narrower

Spinal Muscular Atrophies of Childhood MeSH Descriptor Data 2024