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Aphasia, Primary Progressive MeSH Descriptor Data 2025


MeSH Heading
Aphasia, Primary Progressive
Tree Number(s)
C10.228.140.380.132
C10.597.606.150.500.800.100.155
C23.888.592.604.150.500.800.100.155
F03.615.400.125
Unique ID
D018888
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018888
Annotation
a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports
Scope Note
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
Entry Term(s)
Mesulam Syndrome
Mesulam's Syndrome
Previous Indexing
Aphasia (1982-1995)
Public MeSH Note
1996
History Note
1996
Date Established
1996/01/01
Date of Entry
1994/12/27
Revision Date
2015/06/30
Aphasia, Primary Progressive Preferred
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