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Multiple System Atrophy MeSH Descriptor Data 2025


MeSH Heading
Multiple System Atrophy
Tree Number(s)
C10.177.575.550
C10.228.140.079.612
C10.228.662.550
C10.574.928.625
Unique ID
D019578
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019578
Annotation
a specific neurodegenerative syndrome complex; not for atrophy in other systems
Scope Note
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Entry Term(s)
Multiple System Atrophy Syndrome
Multisystem Atrophy
Multisystemic Atrophy
Previous Indexing
Autonomic Nervous System Diseases (1981-1997)
Brain Diseases (1981-1993)
Nervous System Diseases (1969-1997)
Shy-Drager Syndrome (1981-1997)
See Also
Olivopontocerebellar Atrophies
Shy-Drager Syndrome
Public MeSH Note
1998
History Note
1998
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2019/05/17
Multiple System Atrophy Preferred
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