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Shy-Drager Syndrome MeSH Descriptor Data 2022


MeSH Heading
Shy-Drager Syndrome
Tree Number(s)
C10.177.575.550.750
C10.228.140.079.612.700
C10.228.662.550.700
C14.907.514.741
Unique ID
D012791
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012791
Scope Note
A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)
Entry Term(s)
Autonomic Failure, Progressive
Dysautonomia-Orthostatic Hypotension Syndrome
Idiopathic Orthostatic Hypotension, Shy-Drager Type
Orthostatic Hypotension, Dysautonomic
Syndrome, Dysautonomia-Orthostatic Hypotension
NLM Classification #
WL 358.5
Previous Indexing
Hypotension, Orthostatic (1966-1980)
Nervous System Diseases (1966-1980)
See Also
Multiple System Atrophy
Public MeSH Note
1991; see AUTONOMIC NERVOUS SYSTEM DISEASES 1981-1990
History Note
1991(1981)
Date Established
1991/01/01
Date of Entry
1980/05/12
Revision Date
2019/05/17
Shy-Drager Syndrome Preferred
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