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Prions MeSH Descriptor Data 2022


MeSH Heading
Prions
Tree Number(s)
D12.776.785
Unique ID
D011328
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011328
Scope Note
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
Entry Term(s)
Mink Encephalopathy Virus
Prion
Registry Number
0
NLM Classification #
QU 55
Previous Indexing
PrPSc Proteins (1966-1985)
Viral Proteins (1966-1985)
Public MeSH Note
86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
Online Note
use PRIONS to search MINK ENCEPHALOPATHY VIRUS & TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK 1975-92
History Note
86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
Date Established
1986/01/01
Date of Entry
1985/05/10
Revision Date
2020/05/27
Prions Preferred
Mink Encephalopathy Virus Narrower
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