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Prion Proteins MeSH Descriptor Data 2025


MeSH Heading
Prion Proteins
Tree Number(s)
D09.400.430.890.448.600
D12.776.395.550.448.600
D12.776.543.484.500.625
D12.776.543.550.418.600
D12.776.785.340
Unique ID
D000072002
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072002
Scope Note
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
Entry Term(s)
AltPrP
Alternative Prion Protein
CD230 Antigen
Creutzfeldt-Jakob Disease Protein
Fatal Familial Insomnia Protein
Major Prion Protein
PrP Proteins
Prion Protein
Registry Numbers
0
Previous Indexing
Prions (2006-2016)
Public MeSH Note
2017; for PRION PROTEINS see PRIONS 1991-2016
History Note
2017: for PRION PROTEINS use PRIONS 1991-2016
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2023/03/16
Prion Proteins Preferred
Alternative Prion Protein Related
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