NLM Logo

CD59 Antigens MeSH Descriptor Data 2022


MeSH Heading
CD59 Antigens
Tree Number(s)
D12.776.395.550.448.140
D12.776.543.484.500.140
D12.776.543.550.418.140
Unique ID
D018957
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018957
Scope Note
Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
Entry Term(s)
Antigens, CD59
CD59 Antigen
HRF20
Homologous Restriction Factor 20
MACIF
Membrane Attack Complex Inhibition Factor
Membrane Inhibitor of Reactive Lysis
Protectin
Pharm Action
Complement Inactivating Agents
Registry Number
0
Previous Indexing
Antigens, CD (1990-1995)
Antigens, Differentiation (1989-1991)
Membrane Glycoproteins (1989-1995)
Public MeSH Note
2018; see ANTIGENS, CD59 1996-2017 and CD59 ANTIGEN 1989-1995; CD59 ANTIGEN was indexed under ANTIGENS, CD 1990-1995; under MEMBRANE GLYCOPROTEINS 1989-1995; and under ANTIGENS, DIFFERENTIATION 1989-1991; MEMBRANE ATTACK COMPLEX INHIBITION FACTOR was indexed under PROTEINS 1992-1997 and under BLOOD PROTEINS 1990-1991; PROTECTIN was indexed under ION CHANNELS 1996-1999
History Note
2018 (1990); for PROTECTIN use CATIONIC PROTEIN, URATE-CALCIUM OXALATE STONE 1996-1999
Date Established
1996/01/01
Date of Entry
1995/05/26
Revision Date
2017/06/06
CD59 Antigens Preferred
page delivered in 0.159s