MeSH Browser

MeSH Heading: CD52 Antigen
Tree Number(s): D09.400.430.890.448.190; D12.776.395.550.448.190; D12.776.543.484.500.190; D12.776.543.550.418.190; D23.050.285.022; D23.101.100.943
Unique ID: D000074301
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074301
Scope Note: A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
Entry Term(s): CD52 Protein; CDw52 Antigen; Cambridge Pathology 1 Antigen; Campath-1 Antigen; Campath-1 Receptor; Campath-1H Antigen; HLA-Bw52; HLA-Bw52 Antigen; Lymphocyte Antigen CD52; Lymphocyte Antigen CDw52
Registry Numbers: 0
Previous Indexing: Antigens, CD (1991-2017); Antigens, Neoplasm (1991-2017); Glycoproteins (1991-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - GPI-Linked Proteins [D09.400.430.890.448]
        
        Lipopolysaccharide Receptors [D09.400.430.890.448.100]
        
        CD24 Antigen [D09.400.430.890.448.120]
        
        CD55 Antigens [D09.400.430.890.448.130]
        
        CD59 Antigens [D09.400.430.890.448.140]
        
        Bone Marrow Stromal Antigen 2 [D09.400.430.890.448.150]
        
        Carbonic Anhydrase IV [D09.400.430.890.448.160]
        
        CD48 Antigen [D09.400.430.890.448.180]
        
        CD52 Antigen [D09.400.430.890.448.190]
        
        Ciliary Neurotrophic Factor Receptor alpha Subunit [D09.400.430.890.448.200]
        
        Contactins [D09.400.430.890.448.250]
        
        Ephrin-A1 [D09.400.430.890.448.300]
        
        Ephrin-A2 [D09.400.430.890.448.310]
        
        Ephrin-A3 [D09.400.430.890.448.320]
        
        Ephrin-A4 [D09.400.430.890.448.330]
        
        Ephrin-A5 [D09.400.430.890.448.340]
        
        Folate Receptors, GPI-Anchored [D09.400.430.890.448.370]
        
        Glial Cell Line-Derived Neurotrophic Factor Receptors [D09.400.430.890.448.400]
        
        Glypicans [D09.400.430.890.448.500]
        
        Mesothelin [D09.400.430.890.448.550]
        
        Prion Proteins [D09.400.430.890.448.600]
        
        Matrix Metalloproteinase 17 [D09.400.430.890.448.700]
        
        Nogo Receptors [D09.400.430.890.448.738]
        
        Oligodendrocyte-Myelin Glycoprotein [D09.400.430.890.448.775]
        
        Receptors, Urokinase Plasminogen Activator [D09.400.430.890.448.813]
        
        Uromodulin [D09.400.430.890.448.850]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - GPI-Linked Proteins [D12.776.395.550.448]
        
        Lipopolysaccharide Receptors [D12.776.395.550.448.100]
        
        CD24 Antigen [D12.776.395.550.448.120]
        
        CD55 Antigens [D12.776.395.550.448.130]
        
        CD59 Antigens [D12.776.395.550.448.140]
        
        Bone Marrow Stromal Antigen 2 [D12.776.395.550.448.150]
        
        Carbonic Anhydrase IV [D12.776.395.550.448.160]
        
        CD48 Antigen [D12.776.395.550.448.180]
        
        CD52 Antigen [D12.776.395.550.448.190]
        
        Ciliary Neurotrophic Factor Receptor alpha Subunit [D12.776.395.550.448.200]
        
        Contactins [D12.776.395.550.448.250]
        
        Ephrin-A1 [D12.776.395.550.448.300]
        
        Ephrin-A2 [D12.776.395.550.448.310]
        
        Ephrin-A3 [D12.776.395.550.448.320]
        
        Ephrin-A4 [D12.776.395.550.448.330]
        
        Ephrin-A5 [D12.776.395.550.448.340]
        
        Folate Receptors, GPI-Anchored [D12.776.395.550.448.370]
        
        Glial Cell Line-Derived Neurotrophic Factor Receptors [D12.776.395.550.448.400]
        
        Glypicans [D12.776.395.550.448.500]
        
        Mesothelin [D12.776.395.550.448.550]
        
        Prion Proteins [D12.776.395.550.448.600]
        
        Matrix Metalloproteinase 17 [D12.776.395.550.448.700]
        
        Nogo Receptors [D12.776.395.550.448.738]
        
        Oligodendrocyte-Myelin Glycoprotein [D12.776.395.550.448.775]
        
        Receptors, Urokinase Plasminogen Activator [D12.776.395.550.448.813]
        
        Uromodulin [D12.776.395.550.448.850]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Lipid-Linked Proteins [D12.776.543.484]
      - GPI-Linked Proteins [D12.776.543.484.500]
        
        Lipopolysaccharide Receptors [D12.776.543.484.500.100]
        
        CD24 Antigen [D12.776.543.484.500.120]
        
        CD55 Antigens [D12.776.543.484.500.130]
        
        CD59 Antigens [D12.776.543.484.500.140]
        
        Bone Marrow Stromal Antigen 2 [D12.776.543.484.500.150]
        
        Carbonic Anhydrase IV [D12.776.543.484.500.160]
        
        CD48 Antigen [D12.776.543.484.500.180]
        
        CD52 Antigen [D12.776.543.484.500.190]
        
        Ciliary Neurotrophic Factor Receptor alpha Subunit [D12.776.543.484.500.200]
        
        Contactins [D12.776.543.484.500.250]
        
        Ephrin-A1 [D12.776.543.484.500.300]
        
        Ephrin-A2 [D12.776.543.484.500.310]
        
        Ephrin-A3 [D12.776.543.484.500.320]
        
        Ephrin-A4 [D12.776.543.484.500.330]
        
        Ephrin-A5 [D12.776.543.484.500.340]
        
        Folate Receptors, GPI-Anchored [D12.776.543.484.500.370]
        
        Glial Cell Line-Derived Neurotrophic Factor Receptors [D12.776.543.484.500.400]
        
        Glypicans [D12.776.543.484.500.550]
        
        Mesothelin [D12.776.543.484.500.588]
        
        Prion Proteins [D12.776.543.484.500.625]
        
        Matrix Metalloproteinase 17 [D12.776.543.484.500.700]
        
        Nogo Receptors [D12.776.543.484.500.738]
        
        Oligodendrocyte-Myelin Glycoprotein [D12.776.543.484.500.775]
        
        Receptors, Urokinase Plasminogen Activator [D12.776.543.484.500.813]
        
        Uromodulin [D12.776.543.484.500.850]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - GPI-Linked Proteins [D12.776.543.550.418]
        
        Lipopolysaccharide Receptors [D12.776.543.550.418.100]
        
        CD24 Antigen [D12.776.543.550.418.120]
        
        CD55 Antigens [D12.776.543.550.418.130]
        
        CD59 Antigens [D12.776.543.550.418.140]
        
        Bone Marrow Stromal Antigen 2 [D12.776.543.550.418.150]
        
        Carbonic Anhydrase IV [D12.776.543.550.418.160]
        
        CD48 Antigen [D12.776.543.550.418.180]
        
        CD52 Antigen [D12.776.543.550.418.190]
        
        Ciliary Neurotrophic Factor Receptor alpha Subunit [D12.776.543.550.418.200]
        
        Contactins [D12.776.543.550.418.250]
        
        Ephrin-A1 [D12.776.543.550.418.300]
        
        Ephrin-A2 [D12.776.543.550.418.310]
        
        Ephrin-A3 [D12.776.543.550.418.320]
        
        Ephrin-A4 [D12.776.543.550.418.330]
        
        Ephrin-A5 [D12.776.543.550.418.340]
        
        Folate Receptors, GPI-Anchored [D12.776.543.550.418.370]
        
        Glial Cell Line-Derived Neurotrophic Factor Receptors [D12.776.543.550.418.400]
        
        Glypicans [D12.776.543.550.418.500]
        
        Mesothelin [D12.776.543.550.418.550]
        
        Prion Proteins [D12.776.543.550.418.600]
        
        Matrix Metalloproteinase 17 [D12.776.543.550.418.700]
        
        Nogo Receptors [D12.776.543.550.418.738]
        
        Oligodendrocyte-Myelin Glycoprotein [D12.776.543.550.418.775]
        
        Receptors, Urokinase Plasminogen Activator [D12.776.543.550.418.813]
        
        Uromodulin [D12.776.543.550.418.850]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Neoplasm [D23.050.285]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]

CD52 Antigen Preferred

Concept UI: M000626116
Registry Numbers: 0
Scope Note: A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
Terms: CD52 Antigen Preferred Term
Term UI T000915074
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); CDw52 Antigen
Term UI T000915075
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); Campath-1 Antigen
Term UI T000915076
Date02/01/2017
LexicalTag NON
ThesaurusID NLM (2018); Campath-1H Antigen
Term UI T000915077
Date02/01/2017
LexicalTag NON
ThesaurusID NLM (2018); CD52 Protein
Term UI T000915078
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); Lymphocyte Antigen CD52
Term UI T000915080
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); Campath-1 Receptor
Term UI T000915081
Date02/01/2017
LexicalTag NON
ThesaurusID NLM (2018); HLA-Bw52 Antigen
Term UI T000915082
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); HLA-Bw52
Term UI T000915084
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018); Cambridge Pathology 1 Antigen
Term UI T000915073
Date02/01/2017
LexicalTag NON
ThesaurusID NLM (2016); Lymphocyte Antigen CDw52
Term UI T000915085
Date02/01/2017
LexicalTag ABX
ThesaurusID NLM (2018)

CD52 Antigen MeSH Descriptor Data 2024