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Aprotinin MeSH Descriptor Data 2022


MeSH Heading
Aprotinin
Tree Number(s)
D12.776.083
Unique ID
D007611
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007611
Scope Note
A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Entry Term(s)
Antilysin
BPTI, Basic Pancreatic Trypsin Inhibitor
Basic Pancreatic Trypsin Inhibitor
Bovine Kunitz Pancreatic Trypsin Inhibitor
Bovine Pancreatic Trypsin Inhibitor
Contrical
Contrykal
Dilmintal
Iniprol
Kallikrein-Trypsin Inactivator
Kontrikal
Kontrykal
Kunitz Pancreatic Trypsin Inhibitor
Pulmin
Traskolan
Trasylol
Trypsin Inhibitor, Basic, Pancreatic
Trypsin Inhibitor, Kunitz, Pancreatic
Zymofren
Pharm Action
Hemostatics
Trypsin Inhibitors
Serine Proteinase Inhibitors
Registry Number
9087-70-1
Related Numbers
9004-04-0
NLM Classification #
QU 143
Public MeSH Note
90; was KALLIKREIN-TRYPSIN INACTIVATOR 1966-89
Online Note
use APROTININ to search KALLIKREIN-TRYPSIN INACTIVATOR 1966-89
History Note
90; was KALLIKREIN-TRYPSIN INACTIVATOR 1966-89
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/01
Aprotinin Preferred
Pulmin Narrower
Traskolan Narrower
Dilmintal Narrower
Zymofren Narrower
Antilysin Narrower
Contrykal Narrower
Iniprol Narrower
Trasylol Related
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