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Tumor Suppressor Protein p53 MeSH Descriptor Data 2022


MeSH Heading
Tumor Suppressor Protein p53
Tree Number(s)
D12.776.157.687.650
D12.776.260.820
D12.776.624.776.775
D12.776.660.720.650
D12.776.744.845
Unique ID
D016159
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016159
Scope Note
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
Entry Term(s)
Cellular Tumor Antigen p53
Oncoprotein p53
TP53 Protein
TRP53 Protein
p53 Antigen
p53 Tumor Suppressor Protein
pp53 Phosphoprotein
Registry Number
0
Previous Indexing
Neoplasm Proteins (1981-1989)
Oncogene Products (1990)
Phosphoproteins (1981-1990)
Public MeSH Note
2005; see TP53 PROTEIN 1991-2005; TP53 PROTEIN was indexed under NERVE TISSUE PROTEINS & NEOPLASM PROTEINS 1992-1993
History Note
2005(1991);
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2017/05/24
Tumor Suppressor Protein p53 Preferred
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