MeSH Browser

MeSH Heading: Crk-Associated Substrate Protein
Tree Number(s): D12.644.360.024.282; D12.776.157.057.016; D12.776.476.024.316; D12.776.744.425
Unique ID: D050719
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050719
Scope Note: A highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.
Entry Term(s): BCAR1 Protein; BCAR1 p130Cas Protein; Breast Cancer Anti-Estrogen Resistance 1 Protein; CRKAS Protein; Crk-Associated Substrate; p130 Cas Protein; p130 Crk-Associated Substrate; p130Cas Protein
Registry Numbers: 0
Public MeSH Note: 2006; CRK-ASSOCIATED SUBSTRATE was indexed under PROTEINS 2004-2005
History Note: 2006(2004)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/12/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Crk-Associated Substrate Protein MeSH Descriptor Data 2025