NLM Logo

Interferon Regulatory Factor-3 MeSH Descriptor Data 2023


MeSH Heading
Interferon Regulatory Factor-3
Tree Number(s)
D12.644.360.024.302.374
D12.776.157.057.050.374
D12.776.260.504.374
D12.776.476.024.385.374
D12.776.744.562
D12.776.930.332.374
Unique ID
D050838
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050838
Scope Note
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Entry Term(s)
IFN-Regulatory Factor 3
IRF-3 Transcription Factor
Registry Number
0
Public MeSH Note
2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005
History Note
2006(1996)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2015/11/23
Interferon Regulatory Factor-3 Preferred
page delivered in 0.203s