MeSH Browser

MeSH Heading: Integrin-Binding Sialoprotein
Tree Number(s): D09.400.430.950.675; D12.776.395.700.675; D12.776.744.527; D12.776.860.300.562
Unique ID: D058574
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058574
Scope Note: A highly glycosylated and sulfated phosphoprotein that is found almost exclusively in mineralized connective tissues. It is an extracellular matrix protein that binds to hydroxyapatite through polyglutamic acid sequences and mediates cell attachment through an RGD sequence.
Entry Term(s): Bone Sialoprotein; Bone Sialoprotein 2; Bone Sialoprotein II
Public MeSH Note: 2011; INTEGRIN-BINDING SIALOPROTEIN was indexed under SIALOGLYCOPROTEINS 2005-2010, and under GLYCOPROTEINS 1989-2004
History Note: 2011
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0543316
Scope Note: A highly glycosylated and sulfated phosphoprotein that is found almost exclusively in mineralized connective tissues. It is an extracellular matrix protein that binds to hydroxyapatite through polyglutamic acid sequences and mediates cell attachment through an RGD sequence.
Terms: Integrin-Binding Sialoprotein Preferred Term
Term UI T765303
Date02/03/2010
LexicalTag NON
ThesaurusID NLM (2011); Bone Sialoprotein 2
Term UI T765299
Date02/03/2010
LexicalTag NON
ThesaurusID NLM (2011); Bone Sialoprotein II
Term UI T765300
Date02/03/2010
LexicalTag NON
ThesaurusID NLM (2011); Bone Sialoprotein
Term UI T765301
Date02/03/2010
LexicalTag NON
ThesaurusID NLM (2011)

Integrin-Binding Sialoprotein MeSH Descriptor Data 2024