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Small Leucine-Rich Proteoglycans MeSH Descriptor Data 2025


MeSH Heading
Small Leucine-Rich Proteoglycans
Tree Number(s)
D09.400.430.930.875
D09.698.735.700
D12.776.395.650.875
D12.776.860.300.806
Unique ID
D000071232
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071232
Scope Note
A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS.
Entry Term(s)
SLRP Proteoglycan
SLRP Proteoglycans
Small Leucine Rich Proteoglycan
Small Leucine-Rich Proteoglycan
Small Leucine-Rich Repeat Proteoglycan
Small Leucine-Rich Repeat Proteoglycans
Registry Numbers
0
Previous Indexing
Proteoglycans (1996-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2023/03/16
Small Leucine-Rich Proteoglycans Preferred
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