MeSH Browser

MeSH Heading: Nicotinamide-Nucleotide Adenylyltransferase
Tree Number(s): D08.811.913.696.445.600; D12.776.157.687.499; D12.776.660.720.499
Unique ID: D009612
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009612
Scope Note: An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals.
Entry Term(s): ATP-NMN Adenylyltransferase; NAD Pyrophosphorylase; NMN Adenylyltransferase; Nicotinamide Mononucleotide Adenylyltransferase
Related Numbers: 9032-70-6
CAS Type 1 Name: ATP:nicotinamide-nucleotide adenylyltransferase
Previous Indexing: Adenosine Triphosphate (1966-1978); Nicotinamide Mononucleotide (1973-1978); Nucleotidyltransferases (1966-1978); Transferases (1966-1967)
Public MeSH Note: 98; see NMN ADENYLYLTRANSFERASE 1991-97; see NUCLEOTIDYLTRANSFERASES 1979-90
History Note: 98(79)
Date Established: 1991/01/01
Date of Entry: 1978/03/13
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

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drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

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isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

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supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0014930
Related Numbers: 9032-70-6
Scope Note: An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals.
Terms: Nicotinamide-Nucleotide Adenylyltransferase Preferred Term
Term UI T028607
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); ATP-NMN Adenylyltransferase
Term UI T028603
Date05/19/1982
LexicalTag NON
ThesaurusID UNK (19XX); NAD Pyrophosphorylase
Term UI T028604
Date03/13/1978
LexicalTag NON
ThesaurusID UNK (19XX); Nicotinamide Mononucleotide Adenylyltransferase
Term UI T028605
Date03/13/1978
LexicalTag NON
ThesaurusID UNK (19XX); NMN Adenylyltransferase
Term UI T028606
Date12/04/1996
LexicalTag NON
ThesaurusID NLM (1998)

Nicotinamide-Nucleotide Adenylyltransferase MeSH Descriptor Data 2024