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2',5'-Oligoadenylate Synthetase MeSH Descriptor Data 2023


MeSH Heading
2',5'-Oligoadenylate Synthetase
Tree Number(s)
D08.811.913.696.445.625
Unique ID
D015088
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015088
Scope Note
An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.
Entry Term(s)
(2'-5')An Polymerase
2',5'-Oligo(A) Polymerase
2',5'-Oligo(A) Synthetase
2',5'-Oligoadenylate Polymerase
2,5 Oligoadenylate Polymerase
2,5 Oligoadenylate Synthetase
2-5A Synthetase
ATP-(2'-5')oligo(A)adenylyltransferase
Registry Number
EC 2.7.7.84
NLM Classification #
QU 141
Previous Indexing
Nucleotidyltransferases (1966-1982)
Public MeSH Note
83
History Note
83
Date Established
1983/01/01
Date of Entry
1982/05/04
Revision Date
2016/06/29
2',5'-Oligoadenylate Synthetase Preferred
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