MeSH Browser

MeSH Heading: mRNA Guanylyltransferases
Tree Number(s): D08.811.277.352.650.600.800; D08.811.913.696.445.018
Unique ID: D000098556
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000098556
Scope Note: Enzymes that catalyze the transfer of GMP residue from GTP to 5' end of RNA to form a cap structure identified as G(5')pppN. They can also modify synthetic poly(A) & poly(G) to form m7G(5')pppAn & m7G(5')pppGn.
Entry Term(s): GTP mRNA Guanylyltransferase; RNA Guanylyltransferase; m-RNA Guanylyltransferase; mRNA 5'-guanylyltransferase; mRNA Capping Enzyme; mRNA Guanylyltransferase
Registry Numbers: EC 2.7.7.50
Public MeSH Note: 2025; see mRNA GUANYLYLTRANSFERASE 1976-2025; mRNA GUANYLYLTRANSFERASE was indexed under NUCLEOTIDYLTRANSFERASES 1981-2025; RNA, MESSENGER and GUANINE NUCLEOTIDES 1976-1981
History Note: 2025 (1976); was mRNA GUANYLYLTRANSFERASE 1976-2025
Date Established: 2025/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/08/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0077170
Registry Numbers: EC 2.7.7.50
Scope Note: Enzymes that catalyze the transfer of GMP residue from GTP to 5' end of RNA to form a cap structure identified as G(5')pppN. They can also modify synthetic poly(A) & poly(G) to form m7G(5')pppAn & m7G(5')pppGn.
Terms: mRNA Guanylyltransferases Preferred Term
Term UI T001144798
Date08/06/2024
LexicalTag NON
ThesaurusID NLM (2025); GTP mRNA Guanylyltransferase
Term UI T001141383
Date12/08/2023
LexicalTag NON
ThesaurusID NLM (2025); m-RNA Guanylyltransferase
Term UI T107170
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1976); mRNA 5'-guanylyltransferase
Term UI T107171
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1976); mRNA Capping Enzyme
Term UI T001141385
Date12/08/2023
LexicalTag NON
ThesaurusID NLM (2025); mRNA Guanylyltransferase
Term UI T001141382
Date12/08/2023
LexicalTag NON
ThesaurusID NLM (2025); RNA Guanylyltransferase
Term UI T001141384
Date12/08/2023
LexicalTag NON
ThesaurusID NLM (2025)

mRNA Guanylyltransferases MeSH Descriptor Data 2025