Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Inhibitor of Apoptosis Proteins MeSH Descriptor Data 2025


MeSH Heading
Inhibitor of Apoptosis Proteins
Tree Number(s)
D08.811.464.938.750.210
D12.644.360.075.437
D12.776.476.075.437
Unique ID
D051034
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051034
Annotation
APOPTOSIS REGULATORY PROTEINS is also available
Scope Note
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
Entry Term(s)
BIRC2 Protein
Baculoviral IAP Repeat Containing Protein 2
Baculoviral IAP Repeat-Containing 2 Protein
Baculoviral Inhibitor Of Apoptosis Repeat Proteins
Cellular Inhibitor of Apoptosis 1 Protein
IAP Protein (Apoptosis)
IAP Repeat Containing Proteins
IAP2 Protein
Inhibitor of Apoptosis 2 Protein
Inhibitor-Of-Apoptosis Protein
c-IAP1 Protein
cIAP1 Protein
Pharm Action
Caspase Inhibitors
Registry Numbers
0
EC 2.3.2.27
Related Numbers
EC 2.3.2.27
Public MeSH Note
2006; INHIBITOR OF APOPTOSIS PROTEINS was indexed under PROTEINS 1997-2005
History Note
2006(1997)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2017/06/29
Inhibitor of Apoptosis Proteins Preferred
Baculoviral IAP Repeat-Containing 2 Protein Narrower
page delivered in 0.129s