NLM Logo

Lymphocyte Specific Protein Tyrosine Kinase p56(lck) MeSH Descriptor Data 2024


MeSH Heading
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Tree Number(s)
D08.811.913.696.620.682.725.800.315
D12.776.476.568.800.315
D12.776.624.664.700.128
Unique ID
D019860
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019860
Scope Note
This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
Entry Term(s)
Protein Tyrosine Kinase p56(lck)
Proto-Oncogene Protein c-lck
Proto-Oncogene Protein lck
lck Kinase
p56 lck
Previous Indexing
Protein-Tyrosine Kinase (1988-1995)
src-Family Kinases (1996-1997)
Public MeSH Note
98; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK) was indexed under SRC-FAMILY KINASES 1996-97 & PROTEIN-TYROSINE KINASE 1988-95
History Note
98; use LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK) (NM) 1988-97
Date Established
1998/01/01
Date of Entry
1997/07/02
Revision Date
2021/05/21
Lymphocyte Specific Protein Tyrosine Kinase p56(lck) Preferred
page delivered in 0.162s