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Shelterin Complex MeSH Descriptor Data 2022


MeSH Heading
Shelterin Complex
Tree Number(s)
A11.284.430.106.279.345.190.160.845.500
D05.500.918
D12.776.260.735.625
D12.776.660.235.700.625
D12.776.664.981
G05.360.160.845.500
Unique ID
D000089804
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000089804
Scope Note
A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).
Entry Term(s)
CST Complex
Ctc1-Stn1-Ten1 Complex
POT1-TPP1 Shelterin Complex
Telomere Cap Complex
Telomere POT1-TPP1 Complex
Telomeric Capping Complex
Telomeric Stn1-Ten1 Capping Complex
Telosome
Registry Number
0
Previous Indexing
Telomere-Binding Proteins (2005-2021)
Public MeSH Note
2022
History Note
2022
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2021/06/30
Shelterin Complex Preferred
Telomere Cap Complex Related
CST Complex Related
Telomeric Stn1-Ten1 Capping Complex Related
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