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Axin Signaling Complex MeSH Descriptor Data 2022


MeSH Heading
Axin Signaling Complex
Tree Number(s)
D05.500.117
D12.776.476.081
Unique ID
D060465
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D060465
Scope Note
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.
Entry Term(s)
Axin Signaling Complex Proteins
beta-Catenin Destruction Complex
Registry Number
0
Public MeSH Note
2012
History Note
2012
Date Established
2012/01/01
Date of Entry
2011/06/24
Axin Signaling Complex Preferred
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