MeSH Browser

MeSH Heading: Secreted Frizzled-Related Proteins
Tree Number(s): D12.644.360.813; D12.776.476.800; D12.776.543.302.001
Unique ID: D000094742
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000094742
Scope Note: Soluble and secreted frizzled-related proteins which function as modulators of WNT SIGNALING PATHWAY.
Entry Term(s): FRZB Protein; Fritz Protein; Frizzled Related Protein-3; SFRP1 Protein; Secreted Frizzled Related Protein 1; Secreted Frizzled Related Protein-1; Secreted Frizzled Related Protein-3; Sfrp-1 Protein; Soluble Frizzled-Related Proteins; sFRPS
Registry Numbers: 0
Previous Indexing: Intracellular Signaling Peptides and Proteins (1997-2022)
See Also: Frizzled Receptors
Public MeSH Note: 2026; for SECRETED FRIZZLED RELATED PROTEIN-1 see WD REPEAT CONTAINING PLANAR CELL POLARITY EFFECTOR (NM) 1997-2025
History Note: 2026 (2023); for SECRETED FRIZZLED RELATED PROTEIN-1 use WD REPEAT CONTAINING PLANAR CELL POLARITY EFFECTOR (NM) 1997-2025
Date Introduced: 2023/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M000601810
Registry Numbers: 0
Terms: Secreted Frizzled Related Protein 1 Preferred Term
Term UI T001148718
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (2017); Secreted Frizzled Related Protein-1
Term UI T001148719
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (2015); Sfrp-1 Protein
Term UI T001148720
Date05/29/2025
LexicalTag ABX
ThesaurusID NLM (1997); SFRP1 Protein
Term UI T001148726
Date05/29/2025
LexicalTag ABX
ThesaurusID NLM (2026)

Concept UI: M000769086
Terms: Secreted Frizzled Related Protein-3 Preferred Term
Term UI T001148727
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (2000); Fritz Protein
Term UI T001148715
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (1997); Frizzled Related Protein-3
Term UI T001148728
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (2000); FRZB Protein
Term UI T001148717
Date05/29/2025
LexicalTag NON
ThesaurusID NLM (1997)

Secreted Frizzled-Related Proteins MeSH Descriptor Data 2026