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Apoptosomes MeSH Descriptor Data 2022


MeSH Heading
Apoptosomes
Tree Number(s)
D05.500.099
Unique ID
D053478
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053478
Scope Note
Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.
Entry Term(s)
Apoptosomal Protein Complex
Apoptosome
Registry Number
0
Previous Indexing
Apoptosis (1999-2006)
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Apoptosomes Preferred
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