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Apoptosomes MeSH Descriptor Data 2024


MeSH Heading
Apoptosomes
Tree Number(s)
D05.500.099
Unique ID
D053478
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053478
Scope Note
Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.
Entry Term(s)
Apoptosomal Protein Complex
Apoptosome
Previous Indexing
Apoptosis (1999-2006)
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
1955/01/01
Apoptosomes Preferred
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