NLM Logo

Caspase 9 MeSH Descriptor Data 2022


MeSH Heading
Caspase 9
Tree Number(s)
D08.811.277.656.262.500.126.550.900
D08.811.277.656.300.200.126.550.900
D12.776.157.057.006.155
D12.776.476.024.139.155
D12.776.476.075.358.155
D12.776.476.075.405.550.900
Unique ID
D053453
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053453
Annotation
Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9
Scope Note
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Entry Term(s)
Apoptotic Protease Activating Factor 3
Caspase-9
ICE-LAP6 Protein
ICE-Like Apoptotic Protease 6
Pro-Caspase-9
Procaspase-9
Registry Number
EC 3.4.22.-
Public MeSH Note
2007; CASPASE 9 was indexed under CASPASES 1999-2005, & under CYSTEINE PROTEINASES 1996-1998
History Note
2007(2005)
Entry Combination
antagonists & inhibitors:Caspase Inhibitors
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/06/03
Caspase 9 Preferred
Procaspase-9 Narrower
page delivered in 0.147s