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Caspase 10 MeSH Descriptor Data 2022


MeSH Heading
Caspase 10
Tree Number(s)
D08.811.277.656.262.500.126.550.910
D08.811.277.656.300.200.126.550.910
D12.776.476.075.405.550.910
Unique ID
D053455
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053455
Scope Note
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Entry Term(s)
Caspase 10-a
Caspase 10-c
Caspase 10-d
Caspase 10a
Caspase 10c
Caspase 10d
Caspase-10
Mch4 Protease
Registry Number
EC 3.4.22.-
See Also
Autoimmune Lymphoproliferative Syndrome
Public MeSH Note
2007; CASPASE 10 was indexed under CASPASES 1998-2005
History Note
2007(1998)
Entry Combination
antagonists & inhibitors:Caspase Inhibitors
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
Caspase 10 Preferred
Caspase 10c Narrower
Caspase 10d Narrower
Caspase 10a Narrower
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