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Caspase 12 MeSH Descriptor Data 2022


MeSH Heading
Caspase 12
Tree Number(s)
D08.811.277.656.262.500.126.550.920
D08.811.277.656.300.200.126.550.920
D12.776.476.075.405.550.920
Unique ID
D053454
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053454
Scope Note
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Entry Term(s)
Caspase-12
Registry Number
EC 3.4.22.-
Public MeSH Note
2007; CASPASE 12 was indexed under CASPASES 2000-2005
History Note
2007(2000)
Entry Combination
antagonists & inhibitors:Caspase Inhibitors
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
Caspase 12 Preferred
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