Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Entry Term(s)
Messenger RNA
Messenger RNA, Polyadenylated
Non-Polyadenylated mRNA
Poly(A) RNA
Poly(A) Tail
Poly(A)+ RNA
Poly(A)+ mRNA
Polyadenylated mRNA
RNA, Messenger, Polyadenylated
RNA, Polyadenylated
mRNA
mRNA, Non-Polyadenylated
mRNA, Polyadenylated
Registry Numbers
0
NLM Classification #
QU 58.7
Public MeSH Note
65; NON-POLYADENYLATED MRNA was indexed under RNA, MESSENGER 1981-94; POLYADENYLATED MRNA & POLY(A) RNA were indexed under POLY A & RNA, MESSENGER 1980-94
Online Note
use RNA, MESSENGER (NM) to search MRNA, NON-POLYADENYLATED 1981-94, MRNA, POLYADENYLATED 1980-94, & POLY(A)+ RNA 1980-94
History Note
65(64); MRNA, NON-POLYADENYLATED was NON-POLYADENYLATED MRNA (NM) 1981-94; MRNA, POLYADENYLATED was POLYADENYLATED MRNA (NM) 1980-94; POLY(A)+ RNA was SY to POLY(A) RNA (NM) 1980-94
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.