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RNA Caps MeSH Descriptor Data 2022


MeSH Heading
RNA Caps
Tree Number(s)
D03.633.100.759.646.454.700
D13.444.735.544.500
D13.695.667.454.700
D13.695.827.426.700
Unique ID
D012315
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012315
Annotation
IM; /‌drug eff /‌ultrastruct permitted
Scope Note
Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis.
Entry Term(s)
5' Capped RNA
5' mRNA Cap Structure
RNA Cap
Registry Number
0
NLM Classification #
QU 58.7
Previous Indexing
Guanine Nucleotides (1966-1971)
Guanosine Triphosphate (1972-1974)/analogs & derivatives (1975-1979)
Oligoribonucleotides (1976-1979)
RNA, Messenger (1966-1979)
Ribonucleotides (1971-1975)
Public MeSH Note
80
History Note
80
Entry Combination
analogs & derivatives:RNA Cap Analogs
Date Established
1980/01/01
Date of Entry
1979/05/23
Revision Date
2021/06/30
RNA Caps Preferred
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