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Guanosine Tetraphosphate MeSH Descriptor Data 2025


MeSH Heading
Guanosine Tetraphosphate
Tree Number(s)
D03.633.100.759.646.454.480
D13.695.667.454.480
D13.695.827.426.480
Unique ID
D006159
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006159
Scope Note
Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.
Entry Term(s)
Alarmone ppGpp
Bacterial Magic Spot ppGpp
Guanosine 3'-Diphosphate 5'-Diphosphate
Guanosine 5'-(trihydrogen diphosphate), mono(trihydrogen diphosphate) (ester)
Guanosine 5'-Diphosphate 3'-Diphosphate
Guanosine 5'-diphosphate 2'(3')-diphosphate
ppGpp
Registry Numbers
33503-72-9
Previous Indexing
Guanine Nucleotides (1966-1977)
Public MeSH Note
91; was see under GUANINE NUCLEOTIDES 1978-90
History Note
91(78); was see under GUANINE NUCLEOTIDES 1978-90
Date Established
1991/01/01
Date of Entry
1977/04/22
Revision Date
2020/02/28
Guanosine Tetraphosphate Preferred
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